The detailed report on Singapore’s multi-faceted approach at containing and investigating last year’s Zika outbreak has finally been published online at Lancet Infectious Diseases. I had written superficially about some of the events in a series of blog posts at that time, but this published work describes comprehensively both the clinical and public health aspects of managing […]

When the SGH Microbiology blogger (or his team) posted notice on Facebook of the following paper by The Chinese University of Hong Kong investigators, it reminded me of a conversation with that contemplative microbiologist a couple of years ago about hepatitis E. This work from Hong Kong was published in Journal of Clinical Microbiology in February […]

One has to appreciate the messiness that results from science and research during the initial phase of evidence gathering. Just after the letter in NEJM describing the lack of resurgence of microcephaly cases in Brazil in 2016, the U.S. CDC published data from their Zika Pregnancy Registry, showing in a paper published on 4th April in the […]

When I started work as a doctor, dengue was not as common as it is today, and it was alarming to watch the platelet counts crash during the course of the infection. Senior hospitalists would routinely leave standing orders for platelet transfusions, usually once the platelet count of the patients had fallen below some arbitrary […]

The mainstream media reported a new “cluster” of Zika cases in Singapore yesterday. This involved a couple living in Hougang who almost certainly were infected by local mosquitoes. NEA/MOH were notified on 27th March and a helpful map of the cluster is provided on the NEA website.   In general, perhaps because the clinical disease […]

This article (photos below) was published in our mainstream Chinese newspaper Lianhe Zaobao on 21st February. A small part of it revolves around the utility of antibiotics for these predominantly viral illnesses – many thanks to my ex-classmate Dr Wan Sin Hoe for providing the public education! I personally think it is great that such “unattractive” […]

I spent a pleasant afternoon yesterday listening to various presentations on completed and semi-completed projects at the SIDI Research Symposium at Waterfront Copthorne (Declaration: I am the current director of the Singapore Infectious Diseases Initiative, or SIDI for short). The projects were very diverse in nature, ranging from basic science to clinical research as well […]