There are a series of clinical trials published this year that challenge long-held notions in the treatment of infectious diseases. When I was a trainee, we routinely prescribe high-dose intravenous antibiotics for prolonged periods of 4 to 6 weeks for infective endocarditis (infection of the heart valves), because the conventional understanding was that high concentrations […]
I was invited to give this talk at the ECHO Singapore 2018 conference last Saturday, and had to do a bit of reading up. Who should receive antibiotic prophylaxis against endocarditis, particularly when undergoing dental procedures, is obviously an important clinical decision. Endocarditis – inflammation of the inner layer of the heart, particularly the heart […]
An elderly man presented with fever and malaise for a week followed by right buttock pain which was worse on sitting for 2 days. He has well-controlled hypertension and ischemic heart disease. An X-ray of the lumbosacral spine showed narrowing of the L2-L3 disc space following which an MRI of the spine was arranged. Blood […]
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