Dengvaxia (CYD-TDV) – the first licensed dengue vaccine – is a quadrivalent live attenuated chimeric dengue vaccine developed by Sanofi Pasteur. An attenuated yellow fever virus forms the backbone of the vaccine, with dengue structural proteins attached (the chimera). It has just been licensed in Singapore, and is approved for use in those between the ages […]

The report on the summit organised by the Wellcome Trust in April 2016 to discuss evidence surrounding various policy recommendations for controlling antimicrobial resistance has been published. Policy makers and researchers from 27 countries participated. Three areas for immediate policy action were identified and highlighted: Antibiotic use in agriculture has to be reduced, but without […]

Held jointly with the 11th Singapore Public Health & Occupational Medicine Conference at the Waterfront Copthorne Hotel. I managed to attend the opening and initial lectures yesterday morning. Dr Amy Khor, the Senior Minister of State, Ministry of the Environment and Water Resources & Ministry of Health, was once again the guest of honour (as […]

The Zika epidemic in Singapore appears to be progressing towards endemicity. As of yesterday, there are 387 confirmed cases, with 9 clusters. Among the confirmed cases are 16 pregnant women, and the Ministry of Health has announced plans to set up a national surveillance programme to monitor the development of babies born to these and […]

Approximately 11 hours from now, the United Nation General Assembly will host a “high level meeting” on antimicrobial resistance at the UN headquarters in New York. There will be statements by the UN secretary-general and the director-generals of the World Health Organization (WHO), Food and Agricultural Organization of the UN (FAO) and World Organization for […]

Today’s addition of 16 new cases of Zika infection – the smallest number added for the past week – brings the total number of confirmed Zika infections to 258. No links to prior clusters were found in 4 cases. It is too soon to know whether this drop in cases reported represents a blip or if […]

The Ministry of Health Singapore (MOH) released a joint statement last night that included a short statement about the sequencing results of the viruses obtained from two patients from Sim’s Drive. What was of interest was the claim that “the (local) virus belongs to the Asian lineage and likely evolved from the strain that was […]

Following press reports, the Zika epidemic in Singapore has expanded rapidly since it was first reported in the news 6 days ago. There are now 153 cases reported as of yesterday, including two pregnant women. There is also a separate cluster of Zika infections outside of the original Sims Drive/Aljunied Crescent area, at Bedok North Avenue 3. […]

Took a truncated hiatus from Zika to attend the 17th International Sympsium on Staphylococci and Staphylococcal Infections held at the Nine Tree Convention Centre in Seoul, Korea. It’s a rather quaint and unique conference, centered around one single bacterial genus (but it’s almost all about Staphylococcus aureus and MRSA), held every two years rotating between […]

The second case of Zika infection occurred in a woman with no recent history of travel, suggesting that the virus has started to spread locally. Three others living or working near her workplace has also tested positive, according to the Straits Times report. It is important to keep in mind that approximately 80% of Zika […]