A middle-aged man was recently diagnosed with poor prognosis myelodysplastic syndrome (MDS). He was prescribed a course of subcutaneous azacitidine. One week after the first cycle (7 days) of the drug, he presented with pain over the injection sites (over his anterior abdominal wall), associated with high fever and weight loss. He was admitted to […]
I received the Ministry of Health Clinical Practice Guidelines (CPG) for tuberculosis a couple of weeks ago. The full version is also available on the MOH website here. Mixed feelings. There is always a bit of pride at having contributed to such things. Having sat in on the meetings, I am also aware of the […]
A late middle-aged man with advanced lung cancer was switched to 3-weekly pembrolizumab after his malignancy progressed through multiple courses of chemotherapy. Pet CT at 12 weeks showed stable disease. However, he presented with sudden onset fever, worsening cough, and breathlessness after 6 months of immunotherapy. There was no contact or travel history of note, […]
The Review on Antimicrobial Resistance was commissioned in July 2014 by the U.K. government to analyse the global problem of antimicrobial resistance and to propose concrete steps to deal with it. A remarkably enlightened move, I may add, given that U.K is not actually one of the countries with high rates of antimicrobial resistance, and […]
The first case of imported Zika infection in Singapore was announced on the mainstream media yesterday – a Singaporean permanent resident who had traveled to Sao Paulo, Brazil between 27th March and 7th May and who had developed symptoms on 10th May. According to the news report, he is recovering (Zika causes mild disease in […]
Six-time Singapore National Chess Champion and Singapore No.2 (No.1 is Grandmaster Zhang Zhong who was formerly one of the top players of China) Goh Wei Ming has just written a long post on his blog about his decision not to be a part of any Singapore chess team under the current Singapore Chess Federation (SCF) […]
It has been more than two weeks since the story first broke on mainstream media. More than a hundred additional cases have been linked to the durian pastry outbreak (bringing the total to at least 183 cases), while the Goodwood Park Hotel bakery remains suspended. The initial investigation was reportedly performed from 4th April (i.e. […]
MIPHIDIC 