A middle-aged man presented with a low-grade fever (37.8 degrees Celsius) and sudden pain over his right thigh for 3 days, which did not resolve with painkillers. He has a history of diabetes mellitus, and had a road traffic accident 30 years ago resulting in the fracture of his right femur. This was repaired (open reduction […]

After the excitement of the second and third games, the next two games seemed almost prosaic in comparison. Carlsen went for his usual “playable position with no advantage” as White in Game 4 (it can be viewed here at the Chessbase site), playing a quiet line against the Sicilian, but was unable to achieve anything significant. […]

A fantastic game from Anand, who bounced back from a depressing Round 2 loss. His team had certainly out-prepared Carlsen’s in this Queen’s Gambit Declined, and he didn’t give Carlsen a chance to wriggle out of the sharp position with its ensuing complications. This is Anand at his best – something that hasn’t been seen […]

The games are available at multiple sites, although the reports on Chessbase come with game commentary and slight analysis (Games 1 and 2 respective). Carlsen is already in the lead after winning the second game, and unless Anand somehow manages to lift his game, the overall match prospects look dim for him. Game 1 was […]

The Chessdom website will provide live updates on the opening ceremony (today) and the games that will commence from tomorrow. The World Chess Championship is held in Sochi, Russia, and many pundits and grandmasters have given their predictions about the match. An excerpt of GM Sergei Shipov’s opinions of the match is also available on […]

An elderly man from Indonesia presented with loss of appetite and weight for 6 weeks, with fever and night sweats for the last 2 weeks. He had no contact history of note, and was previously well. Clinical examination was unremarkable except for a temperature of 38.3 degrees Celsius. His chest X-ray and a representative cut from the […]

What do disparate parts of the world such as Denmark, Sweden, Norway, Holland, Western Australia, and other Scandinavian countries have in common? From an infectious diseases perspective, they all have similarly low rates of healthcare-associated MRSA (and other antibiotic-resistant bacteria) despite being developed countries/regions with sophisticated healthcare. Denmark’s success in controlling healthcare-associated MRSA despite initial […]

There has been considerable variability in terms of MRSA control in hospitals around the world. This can perhaps be best shown if one looks at the antimicrobial resistance surveillance report published by the European CDC (latest = 2012). I have taken the liberty to copy the relevant diagram (below). It can be seen that the […]

Antimicrobial stewardship generally refers to hospital-based programs that attempt to improve the use of antimicrobial agents. These programs have arisen in large part because of the growing problem of antimicrobial resistance, and the sad (but entirely logical) recognition that antibiotic prescription guidelines are insufficient for improving antibiotic use and often poorly implemented. Appropriate antibiotic prescription […]

A middle-aged man presented with acute lymphoblastic leukemia (initial white cell count of 150,000 per cubic millimetre of blood – mostly blasts). After completing a course of hyper-CVAD, he developed persistent febrile neutropenia that was unresponsive to antibiotics. On the 6th day of fever, CT thorax was performed which was normal. On the 8th day […]