Two days ago, our paper on the “Evolution dynamics of methicillin-resistant Staphylococcus aureus in a healthcare system” was published in the BiomedCentral journal Genome Biology. We sequenced the genomes of 260 clinical MRSA isolates cultured over 3 decades (1982 to 2010) in four Singaporean hospitals – a number that seemed really high back in 2011, but […]

A timeline movie of different MRSA clones discovered in Singapore. The movie unfortunately plays rather slowly (just over a minute). More detailed descriptions will be provided in subsequent blog posts.

I came across this site via a search on “superbugs” on Google News. The UK review team was commissioned by the UK Prime Minister in July 2014, and published its first report about 2 weeks ago. By the end of 2 years – summer 2016 – the Review will have to propose a package of […]

After a period of 6-7 years of “rational MRSA control’ targeted towards MRSA containment rather than eradication, many Singaporean public sector hospitals stepped up efforts to reduce their MRSA burden again. While it was clear that the infection control staff from different hospitals were communicating with each other, there was no overall or coordinated strategy among […]

I promised in an earlier post to discuss what I felt was the first major anti-MRSA campaign in Singapore. Although it occurred not too long ago (estimated 1994/5 – 1998/9), there are no easily obtainable records of what transpired, and I only started work right at the tail end of the “campaign” – at that […]

Methicillin-resistant Staphylococcus aureus (MRSA) probably emerged in Singaporean hospitals in the 1970’s. The exact date, and whether the first isolates were imported from overseas or arose from within Singapore’s own S. aureus population is no longer known (or at least I have not been able to find someone who has a clear recollection of these events). We do have […]

A middle-aged man presented with a low-grade fever (37.8 degrees Celsius) and sudden pain over his right thigh for 3 days, which did not resolve with painkillers. He has a history of diabetes mellitus, and had a road traffic accident 30 years ago resulting in the fracture of his right femur. This was repaired (open reduction […]