After a period of 6-7 years of “rational MRSA control’ targeted towards MRSA containment rather than eradication, many Singaporean public sector hospitals stepped up efforts to reduce their MRSA burden again. While it was clear that the infection control staff from different hospitals were communicating with each other, there was no overall or coordinated strategy among […]

I promised in an earlier post to discuss what I felt was the first major anti-MRSA campaign in Singapore. Although it occurred not too long ago (estimated 1994/5 – 1998/9), there are no easily obtainable records of what transpired, and I only started work right at the tail end of the “campaign” – at that […]

Methicillin-resistant Staphylococcus aureus (MRSA) probably emerged in Singaporean hospitals in the 1970’s. The exact date, and whether the first isolates were imported from overseas or arose from within Singapore’s own S. aureus population is no longer known (or at least I have not been able to find someone who has a clear recollection of these events). We do have […]

A middle-aged man presented with a low-grade fever (37.8 degrees Celsius) and sudden pain over his right thigh for 3 days, which did not resolve with painkillers. He has a history of diabetes mellitus, and had a road traffic accident 30 years ago resulting in the fracture of his right femur. This was repaired (open reduction […]

What do disparate parts of the world such as Denmark, Sweden, Norway, Holland, Western Australia, and other Scandinavian countries have in common? From an infectious diseases perspective, they all have similarly low rates of healthcare-associated MRSA (and other antibiotic-resistant bacteria) despite being developed countries/regions with sophisticated healthcare. Denmark’s success in controlling healthcare-associated MRSA despite initial […]

There has been considerable variability in terms of MRSA control in hospitals around the world. This can perhaps be best shown if one looks at the antimicrobial resistance surveillance report published by the European CDC (latest = 2012). I have taken the liberty to copy the relevant diagram (below). It can be seen that the […]

The Gram-positive bacteria Staphylococcus aureus was first discovered by Scottish surgeon Sir Alexander Ogston in his garden shed “laboratory” in 1881 (the short Wikipedia article on his discovery of S. aureus makes for quite interesting reading). It is a human commensal and an opportunistic pathogen, colonizing approximately a third of all humans, particularly those with certain conditions such as […]